Scientists have discovered an anti-inflammatory compound in marijuana that does not affect the brain, meaning it will not produce the same psychotropic effects as the plant's better-known anti-inflammatory component, THC. Researchers say that another cannabinoid, called beta-caryophyllene, or (E)-BCP, is already found in food items like black pepper and oregano, and could treat pain, nausea, and other ailments without getting patients high.
Scientists said that (E)-BCP could potentially be a "New model [compound] for drug design." By targeting the CB-2 receptor, found in tissues throughout the body but not in the brain, as opposed to the CB-1 also targeted by THC, (E)-BCP reduces inflammation without psychotropic effects.
"Targeting the CB2 receptor could be a therapeutic strategy to prevent or treat diseases like Crohn's disease [inflammation of the intestinal tract], liver cirrhosis, osteoarthritis, and atherosclerosis," said lead study author Jürg Gertsch. Other conditions for which medical marijuana may be beneficial include Multiple Sclerosis, glaucoma, cancer, and chronic pain.
